Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disorder where soft tissues gradually turn into bone. Often called the “Stone Man” disease, FOP can severely restrict movement as muscles, tendons, and ligaments harden over time.

Symptoms usually appear in childhood, with minor injuries often triggering rapid bone formation. The condition is caused by a mutation in the ACVR1 gene, but treatments remain limited. Avoiding unnecessary surgeries is critical, as procedures can worsen the disease.

Though extremely rare, FOP has attracted attention in medical research. Scientists hope gene therapy and novel drugs could slow or stop the abnormal bone growth. For now, supportive care and preventive strategies are vital. Patients often rely on adaptive tools, physical therapy, and strong support networks to maintain independence.